hGHRH(1-32)NH2 vs hGHRH(1-40)OH
Head-to-head comparison of hGHRH(1-32)NH2 (Human growth hormone-releasing factor (1-32) amide) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | hGHRH(1-32)NH2 | hGHRH(1-40)OH |
|---|---|---|
| Category | Growth Hormone | Growth Hormone |
| Full Name | Human growth hormone-releasing factor (1-32) amide | Human growth hormone-releasing factor (1-40) hydroxyl |
| Molecular Weight | N/A | N/A |
| Half-Life | 5-15 minutes | 5-20 minutes |
| Amino Acids | 32 | 40 |
| Typical Dose | 0.1-1 mcg/kg | 1-2 mcg/kg |
| Route | Subcutaneous/IV | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 50 | 85 |
| Research Status | Clinical Research | Clinical Research |
hGHRH(1-32)NH2 Benefits
- ✓GH pulse induction
- ✓core-sequence testing
- ✓receptor signaling studies
- ✓protease-resistance comparisons
hGHRH(1-40)OH Benefits
- ✓GH secretion research
- ✓fragment-activity comparison
- ✓receptor binding studies
- ✓axis physiology modeling
hGHRH(1-32)NH2 Dosing
0.1-1 mcg/kg SC or IV bolus|acute GH-response testing with timed blood draws|pulsatile dosing in receptor studies
hGHRH(1-40)OH Dosing
1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies
hGHRH(1-32)NH2 Side Effects
- ⚠headache
- ⚠flushing
- ⚠injection-site irritation
hGHRH(1-40)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠lightheadedness
Research Overview
hGHRH(1-32)NH2
Human GHRF(1-32)NH2 is used in basic and translational studies to evaluate how the active N-terminal region of GHRH drives pituitary hormone release. It helps define the lower bound of sequence length needed for meaningful biological activity.
hGHRH(1-40)OH
Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.
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