Cetrorelix vs hCG
Head-to-head comparison of Cetrorelix (Cetrorelix acetate) and hCG (Human Chorionic Gonadotropin) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Cetrorelix | hCG |
|---|---|---|
| Category | Sexual Health | Sexual Health |
| Full Name | Cetrorelix acetate | Human Chorionic Gonadotropin |
| Molecular Weight | 1431.06 Da | 36,700 Da |
| Half-Life | ~30 hours | ~24-36 hours |
| Amino Acids | 10 | N/A |
| Typical Dose | 0.25 mg SC daily | 500-2,000 IU per dose |
| Route | Subcutaneous | Subcutaneous/Intramuscular |
| Purity | ≥98% | ≥98% |
| Studies Count | 300 | 2000 |
| Research Status | Clinical | Clinical |
Cetrorelix Benefits
- ✓prevents premature ovulation
- ✓supports IVF cycle control
- ✓blocks LH surge
- ✓short-acting pituitary suppression
hCG Benefits
- ✓stimulates endogenous testosterone
- ✓supports spermatogenesis
- ✓preserves testicular volume
- ✓may improve fertility markers
Cetrorelix Dosing
0.25 mg SC daily|start on stimulation day 5-6|protocol-dependent antagonist cycle
hCG Dosing
500-2,000 IU SC/IM 2-3x weekly|1,500-3,000 IU weekly in fertility protocols|titrate to testosterone, estradiol, and semen parameters
Cetrorelix Side Effects
- ⚠injection-site reactions
- ⚠headache
- ⚠nausea
hCG Side Effects
- ⚠acne
- ⚠gynecomastia
- ⚠water retention
Research Overview
Cetrorelix
Cetrorelix is a cornerstone GnRH antagonist in assisted reproduction, with a fast onset and reversible suppression of LH. Trials show it improves cycle management by reducing premature ovulation during stimulation.
hCG
Human studies show hCG can raise intratesticular and serum testosterone by mimicking luteinizing hormone at the testis. It is commonly studied in male hypogonadism and fertility-preservation settings.
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