Bremelanotide vs Omentin-1

Head-to-head comparison of Bremelanotide (Bremelanotide (PT-141), cyclic melanocortin receptor agonist) and Omentin-1 (Omentin-1 (Intelectin-1, ITLN1)) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyBremelanotideOmentin-1
CategorySexual HealthDiabetes & Metabolic
Full NameBremelanotide (PT-141), cyclic melanocortin receptor agonistOmentin-1 (Intelectin-1, ITLN1)
Molecular Weight1025.2 Da~35 kDa
Half-Lifeabout 2.7 hhours
Amino Acids7313
Typical Dose1.75 mgNo approved human dose; research use only
RouteSubcutaneousIV|SC
Purity≥98%≥98%
Studies Count20082
Research StatusClinicalPre-clinical

Bremelanotide Benefits

  • increases sexual desire
  • supports arousal
  • may improve erectile response
  • on-demand use

Omentin-1 Benefits

  • insulin sensitivity
  • glucose uptake
  • lipid handling

Bremelanotide Dosing

1.75 mg subcutaneous PRN|administer about 45 minutes before activity|max 1 dose per 24 hours

Omentin-1 Dosing

not established|not established

Bremelanotide Side Effects

  • nausea
  • flushing
  • headache
  • transient blood pressure increase

Omentin-1 Side Effects

  • unknown
  • immunogenicity risk

Research Overview

Bremelanotide

Human studies and approval data support meaningful effects on sexual desire in women, with a central mechanism involving melanocortin signaling. It is one of the most clinically relevant peptides in this category and is commonly used as the reference compound for PT-141-type research.

Omentin-1

Lower omentin-1 levels are often associated with obesity, insulin resistance, and metabolic syndrome. Research continues on its use as a biomarker and as a mechanistic lead for AMPK-linked metabolic interventions.

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Common Stacking Partners

Bremelanotide stacks with:

Kisspeptin-54Melanotan-II

Omentin-1 stacks with:

Intelectin-1ITLN1
melanocortinlibidoerectile-functionapprovedAMPKadipokineinsulin-sensitizingbiomarker