5-Amino-1MQ vs Hexarelin
Head-to-head comparison of 5-Amino-1MQ (5-Amino-1-methylquinolinium) and Hexarelin (Growth Hormone Releasing Hexapeptide) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | 5-Amino-1MQ | Hexarelin |
|---|---|---|
| Category | Weight Management | Performance |
| Full Name | 5-Amino-1-methylquinolinium | Growth Hormone Releasing Hexapeptide |
| Molecular Weight | 178.23 g/mol | 887.04 Da |
| Half-Life | ~6 hours | ~70 minutes |
| Amino Acids | Small molecule | 6 |
| Typical Dose | — | 100-200 mcg |
| Route | — | SC / IV |
| Purity | >98% | — |
| Studies Count | 28 | 198 |
| Research Status | Active Research | Clinical Trials |
5-Amino-1MQ Benefits
- ✓Reduces body fat without appetite changes, lowers cholesterol, increases NAD+ levels, improves metabolic efficiency, supports cellular energy production
Hexarelin Benefits
- ✓Strongest GH pulse among GHRPs
- ✓Cardioprotective effects
- ✓Muscle mass and strength gains
- ✓Fat loss through improved body composition
- ✓Enhanced recovery from training
5-Amino-1MQ Dosing
Research doses: 50-150 mg orally daily. Often cycled 8-12 weeks on, 4 weeks off. Best taken in the morning.
Hexarelin Dosing
Standard: 100-200 mcg SC 2-3 times daily|Pre-workout: 100 mcg 30 min before training|Pre-bed: 100 mcg for overnight GH pulse|Cycle: 8-12 weeks then 4 week break (desensitization)
5-Amino-1MQ Side Effects
- ⚠Generally well-tolerated in preclinical models. Potential mild GI discomfort and headache. Long-term human safety data is limited.
Hexarelin Side Effects
- ⚠Common: Increased appetite, water retention, tingling
- ⚠Moderate: Cortisol and prolactin elevation (dose-dependent)
- ⚠Notable: Desensitization occurs after 4-16 weeks of continuous use
- ⚠Rare: Numbness in extremities
Research Overview
5-Amino-1MQ
Studies in diet-induced obese mice showed significant reductions in body weight, white adipose tissue mass, and cholesterol levels without changes in food intake. Works by inhibiting NNMT enzyme to increase NAD+ and activate sirtuins.
Hexarelin
Hexarelin has extensive pre-clinical and clinical evidence. Multiple human studies confirm potent GH release. Unique cardioprotective properties are well-documented. Note that receptor desensitization limits long-term continuous use.
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