5-Amino-1MQ vs hGHRH(1-40)OH
Head-to-head comparison of 5-Amino-1MQ (5-Amino-1-methylquinolinium) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | 5-Amino-1MQ | hGHRH(1-40)OH |
|---|---|---|
| Category | Weight Management | Growth Hormone |
| Full Name | 5-Amino-1-methylquinolinium | Human growth hormone-releasing factor (1-40) hydroxyl |
| Molecular Weight | 178.23 g/mol | N/A |
| Half-Life | ~6 hours | 5-20 minutes |
| Amino Acids | Small molecule | 40 |
| Typical Dose | — | 1-2 mcg/kg |
| Route | — | Subcutaneous/IV |
| Purity | >98% | ≥98% |
| Studies Count | 28 | 85 |
| Research Status | Active Research | Clinical Research |
5-Amino-1MQ Benefits
- ✓Reduces body fat without appetite changes, lowers cholesterol, increases NAD+ levels, improves metabolic efficiency, supports cellular energy production
hGHRH(1-40)OH Benefits
- ✓GH secretion research
- ✓fragment-activity comparison
- ✓receptor binding studies
- ✓axis physiology modeling
5-Amino-1MQ Dosing
Research doses: 50-150 mg orally daily. Often cycled 8-12 weeks on, 4 weeks off. Best taken in the morning.
hGHRH(1-40)OH Dosing
1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies
5-Amino-1MQ Side Effects
- ⚠Generally well-tolerated in preclinical models. Potential mild GI discomfort and headache. Long-term human safety data is limited.
hGHRH(1-40)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠lightheadedness
Research Overview
5-Amino-1MQ
Studies in diet-induced obese mice showed significant reductions in body weight, white adipose tissue mass, and cholesterol levels without changes in food intake. Works by inhibiting NNMT enzyme to increase NAD+ and activate sirtuins.
hGHRH(1-40)OH
Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.
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