Thymopentin vs Thymalin

Head-to-head comparison of Thymopentin (L-Arginyl-L-Lysyl-L-Aspartyl-L-Valyl-L-Tyrosine) and Thymalin (Calf Thymus Peptide Fraction (Thymalin)) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyThymopentinThymalin
CategoryImmune SupportImmune Support
Full NameL-Arginyl-L-Lysyl-L-Aspartyl-L-Valyl-L-TyrosineCalf Thymus Peptide Fraction (Thymalin)
Molecular Weight676.78 DaN/A
Half-Life10-30 minN/A
Amino Acids5N/A
Typical Dose1 mg5-20 mg
RouteSubcutaneousIntramuscular
Purity≥98%≥98%
Studies Count90120
Research StatusClinicalClinical

Thymopentin Benefits

  • t-cell maturation
  • helper-suppressor balance
  • immune recovery
  • antiviral-adjunct research

Thymalin Benefits

  • t-cell support
  • leukocyte recovery
  • immunomodulation
  • infection-resilience

Thymopentin Dosing

1 mg SC or IM|2-3x weekly|4-8 week study cycles

Thymalin Dosing

5-10 mg IM daily|3-10 day cycles|repeat cycles after 1-4 weeks if studied

Thymopentin Side Effects

  • injection-site redness
  • mild fever
  • headache

Thymalin Side Effects

  • injection-site discomfort
  • transient fever
  • rash/allergy

Research Overview

Thymopentin

Thymopentin has a long history of preclinical and clinical investigation as a thymic peptide immunomodulator. Published studies report effects on T-cell subsets, cytokine responses, and immune recovery in recurrent infection settings.

Thymalin

Thymalin appears in Soviet/Russian clinical literature as a thymus peptide complex used to normalize immune parameters after illness, surgery, or radiation exposure. Reports commonly focus on changes in lymphocyte subsets, phagocytic activity, and infection frequency rather than a single isolated peptide mechanism.

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Common Stacking Partners

Thymopentin stacks with:

Vitamin DZincNAC

Thymalin stacks with:

Vitamin DZincProbiotics
thymic-peptidet-cellimmunomodulatorclinical-literature