HGH Fragment 176-191 vs CJC-1295

Head-to-head comparison of HGH Fragment 176-191 (Human Growth Hormone Fragment 176-191) and CJC-1295 (Growth Hormone Releasing Hormone Analog) — benefits, dosing, side effects, research data, and where to buy.

Research Score

PropertyHGH Fragment 176-191CJC-1295
CategoryWeight ManagementPerformance
Full NameHuman Growth Hormone Fragment 176-191Growth Hormone Releasing Hormone Analog
Molecular Weight1817.12 g/mol3,367.97 Da
Half-Life~30 minutes~6-8 days (DAC)
Amino Acids1630
Typical Dose1-2 mg/week
RouteSC
Purity>98%
Studies Count45167
Research StatusActive ResearchClinical Trials

HGH Fragment 176-191 Benefits

  • Targeted fat loss, no blood sugar impact, no IGF-1 elevation, inhibits lipogenesis, stimulates lipolysis, improved body composition

CJC-1295 Benefits

  • Sustained GH release over days
  • Improved body composition
  • Enhanced deep sleep quality
  • Accelerated recovery from training
  • Increased protein synthesis

HGH Fragment 176-191 Dosing

250-500 mcg subcutaneously 1-2 times daily on empty stomach. 12-16 week cycles typical in research.

CJC-1295 Dosing

Without DAC: 100-200 mcg SC 2-3 times daily|With DAC: 1-2 mg SC once or twice weekly|Combined with Ipamorelin: 100 mcg each, 2-3x daily

HGH Fragment 176-191 Side Effects

  • Injection site irritation, headache, drowsiness. Does not affect blood sugar, insulin sensitivity, or elevate IGF-1.

CJC-1295 Side Effects

  • Common (Mild): Water retention, tingling/numbness, flushing
  • Moderate: Joint stiffness, carpal tunnel-like symptoms
  • Rare: Elevated blood sugar (transient)

Research Overview

HGH Fragment 176-191

This 16-amino-acid fragment specifically targets adipose tissue via beta-3 adrenergic receptors. Works through a GH-receptor-independent pathway, explaining selective fat-loss properties without growth-promoting effects.

CJC-1295

CJC-1295 has good pre-clinical and early clinical data. The DAC variant shows sustained GH elevation for days. Often combined with GHRPs for synergistic GH release.

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Common Stacking Partners

HGH Fragment 176-191 stacks with:

AOD-9604CJC-1295Ipamorelin

CJC-1295 stacks with:

IpamorelinGHRP-6BPC-157
fat-lossgrowth-hormone-fragmentlipolysisbody-recompositionGH SecretagoguePerformanceRecoveryAnti-aging