Elamipretide vs hGHRH(1-40)OH
Head-to-head comparison of Elamipretide (Elamipretide (MTP-131, SS-31)) and hGHRH(1-40)OH (Human growth hormone-releasing factor (1-40) hydroxyl) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | Elamipretide | hGHRH(1-40)OH |
|---|---|---|
| Category | Muscle & Performance | Growth Hormone |
| Full Name | Elamipretide (MTP-131, SS-31) | Human growth hormone-releasing factor (1-40) hydroxyl |
| Molecular Weight | 639.8 Da | N/A |
| Half-Life | 1-4 hours | 5-20 minutes |
| Amino Acids | 4 | 40 |
| Typical Dose | 0.01-0.25 mg/kg/day | 1-2 mcg/kg |
| Route | Subcutaneous/Intravenous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 120 | 85 |
| Research Status | Clinical | Clinical Research |
Elamipretide Benefits
- ✓mitochondrial protection
- ✓reduced oxidative stress
- ✓improved fatigue resistance
- ✓may support exercise tolerance
hGHRH(1-40)OH Benefits
- ✓GH secretion research
- ✓fragment-activity comparison
- ✓receptor binding studies
- ✓axis physiology modeling
Elamipretide Dosing
0.01-0.25 mg/kg/day SC (clinical research)|daily dosing in trials|alternative IV protocols in some studies
hGHRH(1-40)OH Dosing
1-2 mcg/kg SC or IV in acute research settings|single-bolus GH stimulation protocols|repeated low-dose administration in comparative studies
Elamipretide Side Effects
- ⚠nausea
- ⚠injection-site reactions
- ⚠diarrhea
- ⚠headache
hGHRH(1-40)OH Side Effects
- ⚠flushing
- ⚠headache
- ⚠lightheadedness
Research Overview
Elamipretide
Clinical and translational studies show elamipretide can improve mitochondrial function and some functional endpoints in mitochondrial disorders. Skeletal muscle research suggests benefits are driven by energy metabolism rather than direct muscle-building effects.
hGHRH(1-40)OH
Human GHRF(1-40)OH has been studied to understand how truncation of the native hormone changes biological potency and half-life. It is a common research tool for mapping minimal active sequences within the GHRH family.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.