BI 456906 vs Oxyntomodulin
Head-to-head comparison of BI 456906 (BI 456906, glucagon-like peptide-1/glucagon receptor dual agonist) and Oxyntomodulin (Endogenous glucagon-like peptide 1 and glucagon co-agonist peptide) — benefits, dosing, side effects, research data, and where to buy.
Research Score
| Property | BI 456906 | Oxyntomodulin |
|---|---|---|
| Category | Weight Management | Weight Management |
| Full Name | BI 456906, glucagon-like peptide-1/glucagon receptor dual agonist | Endogenous glucagon-like peptide 1 and glucagon co-agonist peptide |
| Molecular Weight | N/A | ~4,200 Da |
| Half-Life | Approximately 1 week | 12-15 minutes |
| Amino Acids | N/A | 37 |
| Typical Dose | Trial-dependent; weekly SC dosing | Research doses vary; commonly 100-300 mcg in small human studies |
| Route | Subcutaneous | Subcutaneous/IV |
| Purity | ≥98% | ≥98% |
| Studies Count | 10 | 80 |
| Research Status | Clinical | Clinical |
BI 456906 Benefits
- ✓weight reduction
- ✓improved glucose control
- ✓lower liver-fat burden
- ✓enhanced satiety
Oxyntomodulin Benefits
- ✓reduces appetite
- ✓increases satiety
- ✓supports weight loss
- ✓improves postprandial metabolic signaling
BI 456906 Dosing
once-weekly subcutaneous injection|stepwise titration|ongoing maintenance phase
Oxyntomodulin Dosing
Research-only dosing|Subcutaneous or IV administration in trials|Pair with calorie restriction and monitoring
BI 456906 Side Effects
- ⚠nausea
- ⚠abdominal discomfort
- ⚠diarrhea
Oxyntomodulin Side Effects
- ⚠nausea
- ⚠GI discomfort
- ⚠decreased appetite beyond target
Research Overview
BI 456906
Preclinical and early clinical research support meaningful metabolic effects with a tolerable safety profile. It remains investigational and is not commercially available.
Oxyntomodulin
Human studies showed acute reductions in food intake and modest weight loss, helping establish the GLP-1 and glucagon co-agonism concept. It remains a foundational peptide for obesity and satiety research.
Ready to buy?
Find both peptides from our verified, lab-tested vendors with purity certificates and third-party testing.